2005 Wheelersburg Football Schedule
| Aug. 26 | Ironton | Away | L 6-7 |
| Sept. 2 | Gallipolis | Away | L 30-37 |
| Sept. 9 | Valley | Home | W 27-0 |
| Sept. 16 | Boyd County | Home | W 35-18 |
| Sept. 23 | Minford | Away | W 41-0 |
| Sept. 30 | Portsmouth | Away | W 48-6 |
| Oct. 7 | Waverly | Home | W 41-6 |
| Oct. 14 | Northwest | Away | W 46-0 |
| Oct. 21 | West (Homecoming) | Home | W 14-7 |
| Oct. 28 | Oak Hill | Home | W 34-13 |
| Nov. 6 | Centerburg (playoff 1) | Home | L 10-17 |